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Edexcel IAL·Biology·IAL Biology

Gas Exchange & Haemoglobin

15 min read

Mammalian gas exchange surfaces, the link to surface-area-to-volume ratio, and oxygen transport by haemoglobin including the dissociation curve.

Large active organisms cannot rely on diffusion across the body surface — they have a small surface-area-to-volume (SA:V) ratio — so they need specialised gas exchange surfaces and a transport system.

Features of an efficient gas exchange surface

  • Large surface area (many alveoli) — more diffusion.
  • Thin (one-cell-thick alveolar and capillary walls) — short diffusion distance.
  • Moist — gases dissolve.
  • Good blood supply / ventilation — maintains a steep concentration gradient.

These all follow Fick's law: rate ∝ (surface area × concentration difference) ÷ diffusion distance.

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